Top 20 Cancer Hospitals USA: Cancer is one of the most complex and life-changing medical conditions anyone can face. When it comes to treatment, early detection and the right hospital can significantly impact survival rates and quality of life.
Whether you’re looking for groundbreaking cancer research, advanced therapies, or compassionate care — this guide lists the top 20 cancer hospitals in the U.S. based on:
-
Clinical expertise
-
Cancer survival rates
-
Use of cutting-edge treatments
-
Patient experience
-
U.S. News & World Report rankings
If you or a loved one is battling cancer, this list will help you make the best possible decision for care in 2025.
Why Trust U.S. Cancer Hospitals?
U.S. hospitals are known globally for:
-
Advanced technologies like CAR T-cell therapy, proton therapy, and genomic testing
-
Participation in FDA clinical trials
-
Access to multidisciplinary oncology teams
-
Comprehensive support: palliative care, nutrition, mental health
Top 20 Cancer Hospitals in the USA (2025)
Here’s our expert-curated list of the top 20 hospitals offering world-class oncology care:
1. MD Anderson Cancer Center – Houston, Texas
Ranked #1 in cancer care by U.S. News
-
Specialties: Leukemia, Breast Cancer, Lung Cancer
-
Known For: Personalized treatment plans & immunotherapy leadership
-
Website: mdanderson.org
2. Memorial Sloan Kettering Cancer Center – New York City, NY
-
Oldest private cancer center in the world
-
Pioneers in rare cancers and clinical trials
-
Offers virtual consultations & international services
-
Website: mskcc.org
3. Mayo Clinic – Rochester, Minnesota
-
Ranked among the best in multiple specialties
-
Known for coordinated, team-based care
-
Top for pancreatic and blood cancers
-
Website: mayoclinic.org
4. Dana-Farber Cancer Institute – Boston, Massachusetts
-
Affiliated with Harvard Medical School
-
Excellent for pediatric and adult oncology
-
Strong survivor support programs
-
Website: dana-farber.org
5. Cleveland Clinic – Cleveland, Ohio
-
Renowned for colorectal and lung cancer care
-
Offers second opinions and global patient programs
-
Website: clevelandclinic.org
6. Johns Hopkins Hospital – Baltimore, Maryland
-
Leading in prostate and brain tumor care
-
Offers clinical trials and experimental therapies
-
Website: hopkinsmedicine.org
7. UCLA Jonsson Comprehensive Cancer Center – Los Angeles, CA
-
Specialties: breast, prostate, and skin cancer
-
Cutting-edge radiation and genetic therapy
-
Website: cancer.ucla.edu
8. Stanford Cancer Institute – Stanford, California
-
Offers precision oncology and AI-based cancer diagnostics
-
Affiliated with Stanford University
-
Website: stanfordhealthcare.org
9. Seattle Cancer Care Alliance – Seattle, WA
-
Partnership with Fred Hutchinson & UW Medicine
-
Pioneers in bone marrow transplants
-
Website: seattlecca.org
10. University of Michigan Rogel Cancer Center – Ann Arbor, MI
-
Known for breast and head-neck cancers
-
Emphasis on patient-centered care
-
Website: rogelcancercenter.org
11. Northwestern Medicine Cancer Center – Chicago, IL
-
Offers proton therapy and supportive care
-
Excellent for gastrointestinal cancers
12. City of Hope Comprehensive Cancer Center – Duarte, CA
-
Famous for blood cancer and diabetes-related oncology
-
Cutting-edge cellular therapy programs
13. NYU Langone’s Perlmutter Cancer Center – New York, NY
-
High ratings for personalized cancer treatment
-
Offers leading fertility preservation programs
14. USC Norris Comprehensive Cancer Center – Los Angeles, CA
-
Special focus on immunotherapy and experimental drugs
-
Excellent outcomes in rare tumors
15. Massachusetts General Cancer Center – Boston, MA
-
Top facility for brain and head/neck cancer
-
Uses robotic surgery and AI analytics
16. Emory Winship Cancer Institute – Atlanta, GA
-
Best in Southeast USA for cancer care
-
Access to many NIH clinical trials
17. University of Colorado Cancer Center – Aurora, CO
-
Strong lung and melanoma treatment programs
-
Affiliated with UCHealth
18. Siteman Cancer Center – St. Louis, MO
-
Nationally recognized for lung, breast, and prostate cancer
-
High-tech radiation and surgical oncology units
19. University of Chicago Comprehensive Cancer Center – Chicago, IL
-
Breakthroughs in personalized medicine
-
Offers free second opinions
20. Roswell Park Comprehensive Cancer Center – Buffalo, NY
-
First cancer center in the U.S. (founded in 1898)
-
Known for bladder and pediatric oncology
Choosing the Right Hospital: What to Consider
When selecting a cancer treatment center, evaluate:
-
Specialization in your cancer type
-
Access to clinical trials
-
Quality of support services (nutrition, therapy, etc.)
-
Insurance acceptance
-
Out-of-state or international patient services
-
Survivorship programs
Frequently Asked Questions (FAQs)
Q: Can international patients access care at U.S. cancer hospitals?
Yes. Many top hospitals have global outreach programs with visa, translation, and housing support.
Q: What is the cost of cancer treatment in the USA?
It varies by diagnosis and hospital. Without insurance, treatment can cost between $100,000–$500,000+.Continue
Q: How can I get a second opinion from a U.S. cancer center?Most hospitals offer online consultations or will review your medical reports digitally.
Conclusion
Choosing the right cancer hospital can impact your recovery, survival, and overall health. The USA is home to some of the most advanced and innovative cancer centers in the world, offering the latest technologies and compassionate care.
Whether you’re a U.S. resident or an international patient seeking top-tier cancer care, these 20 hospitals represent the very best in oncology for 2025.